Human TGFβ1

TGFβ1 is a multifunctional cytokine produced by all white blood cell lineages. TGFβ1 functions in differentiation, chemotaxis, proliferation, angiogenesis and activation of many immune cells. Recombinant TGFβ1 human consists of 112 amino acids, 12.32 kDa. Human TGFβ1 is a suitable candidate for different diseases including cancer, tuberculosis, heart disease, multiple sclerosis, obesity and diabetes.

Details

Accession Number: P01137
Quantity:

10ug, 50ug,100ug, 500ug, 1000ug. Core Biogenesis is unlocking the powers of the bioeconomy by ensuring the scalability of world changing technologies as regenerative medicine and cellular agriculture. Contact us directly for lot reservation and (large/bulk/industry/production) quantities.

Origin:

Core- TGFβ1 is produced in plant seeds of Camelina sativa bred in our laboratories in Strasbourg, France.

Species:

Human. Similarity: -Bovine 95% -Porcine 95% -Mouse 90%

Purity:

≥ 95% measured by SDS page, and resolved under reduced (R) and non-reduced (NR) conditions.

Bioactivity:

The biological activity of human recombinant TGFβ1 was determined by inhibition proliferation assay in HT-2 cells. ED50 < 0.1 ng/ml.

Endotoxin Level:

Low endotoxin level ≤ 0.005ng/µg (≤ 0.005EU/ug of protein) as determined by Limulus Amebocyte Lysate assay.

Animal Component-Free:

Xeno-Free Product. Core Biogenesis strictly guarantees that our recombinant proteins have no trace of animal components.

Formulation:

Tris pH 7.4. Our products are shipped in lyophilised format to ensure protein stability in worldwide deliveries.

Preparation:

Due to the hydrophobic nature of TGFβ1 is recommended to reconstitute the protein in 10mM HCL to at least a concentration of 0.1mg/ml. For dilutions, aliquoting and addition of carrier protein please refer to product’s data sheet or get in touch with our technical support team.

Storage:

Reconstituted can be stored at -20ºC or -80ºC for up to 1 year.

Featured Application Areas:

Human TGFβ1 can be used for a wide variety of areas in cell and molecular biology. We provide high purity and bioactive protein with outstanding performance in: -Culture and maintenance of pluripotent stem cells (ESCs and iPSCs). -Differentiation of mesenchymal stem cells (MSCs) into mature chondrocytes. -Generation of regulatory T cells (Tregs).

Publications:

Coming soon! Get in touch if you want to become part of our customer spotlight and get special support for your next paper.

Privacy Preference Center