Through novel protein engineering, FGF-2 STAB® offers an increased half-life and therefore fewer feedings required compared to the wild-type growth factors.
It is significantly more tolerant of heat while maintaining full bioactivity, leading to improved homogeneity in your cell growth.

Derived from our proprietary plant-based production system, FGF-2 STAB® is also fully animal component-free, endotoxin-free, and sustainably produced.

Thanks to the novel nine amino acid substitution, the heat stability of FGF-2 STAB® is
increased compared to wild-type FGF-2. This results in an increase in half-life under
cell culture conditions to 37°C –improving protein stability 10X compared to wild-type.

Historically, researchers and manufacturers have had to maintain a very strict daily feeding schedule during pluripotent stem cell culture to avoid spontaneous differentiation that would degrade the quality of the culture. By nature of its increased half-life and protein stability, FGF-2 STAB® presents a constant exposure of stable growth factor to the cells, affording the developer a much more streamlined feeding schedule and ultimately a more homogenous makeup of your desired phenotype in the final stem cell population.

Realize tangible benefits of FGF-2 STAB® protein stability: significant reductions in the
amount of media required to feed cells, as well as reductions in the number of feedings,
saving labor costs and obviating the need for inconvenient weekend feedings. Refer to
the example feeding schedule and cost comparison of wild-type versus STAB:

FGF-2 STAB® is available in both Research Use Only and cGMP grades. To ensure seamless scale-up, we have ensured that bioactivity and product performance of both grades are equivalent, as both grades are derived from the same molecule.
The cGMP version is augmented with additional quality control testing and documentation to satisfy cGMP cell culture requirements.