Human IL-7

human IL-7, is a hematopoietic growth factor secreted by stromal cells in the bone marrow and thymus. It is also produced by keratinocytes, dendritic cells, hepatocytes, neurons and epithelial cells. IL-7 supports B and T lymphocyte development, proliferation and homeostasis. It also triggers the differentiation of pluripotent hematopoietic stem cells into lymphoid progenitor cells. Recombinant IL-7 human consists of 152 amino acids, 16.72 kDa. Human IL-7 is qualified for different applications including immunotherapy of cancer, during HIV infection or as an hematopoietic stem cell transplant.

Details

Accession Number: P13232
Quantity:

10ug, 50ug,100ug, 500ug, 1000ug. Core Biogenesis is unlocking the powers of the bioeconomy by ensuring the scalability of world changing technologies as regenerative medicine and cellular agriculture. Contact us directly for lot reservation and (large/bulk/industry/production) quantities.

Origin:

IL-7 is produced in plant seeds of Camelina sativa bred in our laboratories in Strasbourg, France.

Species:

Human

Purity:

≥ 95% measured by SDS page, and resolved under reduced (R) and non-reduced (NR) conditions.

Bioactivity:

The biological activity of human recombinant IL-7 cytokine was determined by its ability to promote the proliferation of 2E8 cells. Cell proliferation was measured using non-radioactive colorimetric assay and monitored by absorbance. ED50 < 0.1 ng/ml.

Endotoxin Level:

Low endotoxin level ≤ 0.005ng/µg (≤ 0.005EU/ug of protein) as determined by Limulus Amebocyte Lysate assay.

Animal Component-Free:

Xeno-Free Product. Core Biogenesis strictly guarantees that our recombinant proteins have no trace of animal components.

Formulation:

Tris pH 7.4. Our products are shipped in lyophilised format to ensure protein stability in worldwide deliveries.

Preparation:

It is recommended to reconstitute the protein in sterile water to at least a concentration between 0.05-1.0 mg/ml. For dilutions, aliquoting and addition of carrier protein please refer to product’s data sheet or get in touch with our technical support team.

Storage:

Lyophilised protein is stable at room temperature upon arrival. Once it is reconstituted can be stored at -20ºC or -80ºC for up to 1 year.

Featured Application Areas:

Human IL-7 can be used in a wide variety of experimental and therapeutic workflows in the area of immunology. We provide high purity and bioactive cytokine to support several applications including: -Activation of naive T Cells and differentiated phenotype maintenance.

Publications:

Coming soon! Get in touch if you want to become part of our customer spotlight and get special support for your next paper.

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