Human IL-15

IL-15, is a pleiotropic cytokine secreted by mononuclear phagocytes and is structurally similar to IL-2. IL-15 has a variety of biological functions like the development of inflammatory and protective immune responses to microbial infections and parasites by controlling both the innate and adaptive immune systems. Recombinant IL-15 human consists of 114 amino acids, 12.54 kDa. Human IL-15 is a suitable candidate for vaccine strategies against infectious diseases or in immunotherapy for the metastatic cancer treatment.

Details

Accession Number: P40933
Quantity:

10ug, 50ug,100ug, 500ug, 1000ug. Core Biogenesis is unlocking the powers of the bioeconomy by ensuring the scalability of world changing technologies as regenerative medicine and cellular agriculture. Contact us directly for lot reservation and (large/bulk/industry/production) quantities.

Origin:

IL-15 is produced in plant seeds of Camelina sativa bred in our laboratories in Strasbourg, France.

Species:

Human

Purity:

≥ 95% measured by SDS page, and resolved under reduced (R) and non-reduced (NR) conditions.

Bioactivity:

The biological activity of human recombinant IL-15 cytokine was determined by its ability to promote the proliferation of CTLL-2 cells. Cell proliferation was measured using non-radioactive colorimetric assay and monitored by absorbance. ED50 < 0.1 ng/ml.

Endotoxin Level:

Low endotoxin level ≤ 0.005ng/µg (≤ 0.005EU/ug of protein) as determined by Limulus Amebocyte Lysate assay.

Animal Component-Free:

Xeno-Free Product. Core Biogenesis strictly guarantees that our recombinant proteins have no trace of animal components.

Formulation:

Tris pH 7.4. Our products are shipped in lyophilised format to ensure protein stability in worldwide deliveries.

Preparation:

It is recommended to reconstitute the protein in sterile water to at least a concentration between 0.05-1.0 mg/ml. For dilutions, aliquoting and addition of carrier protein please refer to product’s data sheet or get in touch with our technical support team.

Storage:

Lyophilised protein is stable at room temperature upon arrival. Once it is reconstituted can be stored at -20ºC or -80ºC for up to 1 year.

Featured Application Areas:

Human IL-15 can be used in a wide variety of experimental and therapeutic workflows in the area of immunology. We provide high purity and bioactive cytokine to support several applications including: -Activation and proliferation of T Cells. -Cytotoxic T Cell priming. -Proliferation of Natural Killer (NK) cells.

Publications:

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